Consequently, we kept the title and focus for this handbook, and it is envisioned as a bridge for researchers and a tool to facilitate training of students and technicians in the development and use of numerous transgenic animal model systems.Ĭlearly, much has changed from a technological perspective since the first two editions in 19. This third edition covers technical aspects of gene transfer in animals-from molecular methods to whole animal considerations across a host of species.
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However, aside from the manuals devoted to mouse embryology, a single text illustrating the methodologies employed by leading laboratories in their respective disciplines had not previously been compiled prior to the first edition of this text. There are many general reviews on the topic of animal transgenesis and genetic engineering that are indeed very useful and timely. And yes, as transgenic methodologies continue to evolve, they have dramatically influenced a cross section of disciplines and are recognized as instrumental in expanding our understanding of gene expression, regulation, and function. The questions to be addressed span the scientific spectrum from biomedical and biological applications to production agriculture. Was transgenic now a limiting term? Were the embryological, animal husbandry, reproductive biology, and molecular techniques something that should be highlighted in some bolder fashion? Yet it remained true that transgenic animal technologies and the ability to introduce and modify functional genes in animal models continue to represent powerful, dynamic, and evolving tools for dissecting complex biological processes. It has, after all, been over two decades since the original title was established. In discussions regarding the third edition of Transgenic Animal Technology: A Laboratory Handbook, we wrestled with the changing tide of technologies and a revision of the title for 2014. He was elected a fellow of the American Association for the Advancement of Science (AAAS) in 2011.
He was a Sigma Xi national lecturer from 1993-1995 and a recipient of the 1997 Doerenkamp-Zbinden Foundation Research Prize (awarded for biomedical research that significantly impacts on the welfare and well-being of animals used in research). His research was funded by NIH, USDA, NSF, private foundations and industry. He served as an editor of Transgenic Research on the editorial boards of five others. His laboratory developed a number of enabling technologies for the genetic engineering of both nuclear and mitochondrial genomes, as well as mitochondrial modeling strategies to address human developmental and metabolic diseases. He has published extensively on transgenic modeling, reproductive biology, and embryology of laboratory and domestic animals. For over 30 years, his research revolved around animal modeling and transgenesis. from the University of Georgia and was a postdoctoral fellow at the University of Pennsylvania. Pinkert joined the University of Alabama (UA) in 2013 where he serves as Vice President for Research and Economic Development, and where he is a tenured Professor in the Department of Biological Sciences in the College of Arts and Sciences.
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